日老兵揭慰安妇罪行：士兵排队泄欲像等着上厕所
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What are researchers on heart health working on to transform patient care and prolong lives?
The latest research on skin health
Emerging imaging technologies in brain research
How are advances in women’s health research changing our understanding of basic human biology?
Webinars
27
Aug
2025
The human skin is home to a diverse community of microbes that, far from being passive passengers, actively shape our biology. Recent discoveries reveal that these commensal organisms are not only tolerated by the immune system—they engage with it in surprisingly specific and sophisticated ways.
In this webinar, two leading researchers will explore how skin-resident microbes influence immune responses both locally and systemically, challenging long-standing assumptions about how immunity is trained and maintained. Featuring Michael Fischbach and the 2025 NOSTER & Science Microbiome Prize winner, this webinar will highlight new research showing how our immune system builds a preemptive relationship with beneficial microbes—and how these interactions may be harnessed for therapeutic innovation.
From fundamental immunology to translational applications, this discussion will offer insights relevant to scientists across microbiology, immunology, systems biology, bioengineering, and translational medicine.
Participants will:
- Gain a deeper understanding of how commensal microbes on the skin shape immune responses and why the immune system invests heavily in surveilling the microbiome—even in the absence of infection.
- Explore how insights from commensal–host interactions are informing new approaches to immunotherapy and vaccine development.
- Consider broader implications for translational research, including how host–microbiome relationships may be leveraged to enhance human health, accelerate drug development, and inform personalized medicine.
The webinar is expected to run for about 60 minutes.
27
Aug
2025
14
Aug
2025
Caregivers of individuals with rare diseases often face unique challenges that can feel isolating, both in terms of the medical complexities they manage and the emotional burden they carry. However, many caregivers are finding strength in community, both within their own disease type and across different disease types, as they share experiences, offer support, and advocate for their loved ones. This panel will explore the diverse strategies caregivers use to form and maintain communities—both in-person and online—and how these communities can provide critical emotional, informational, and practical support. We’ll discuss the similarities and differences between in-person and virtual networks, highlighting the unique benefits and challenges each offers. Additionally, the panel will address the important role mental health plays in the caregiver experience, examining how caregiving can affect mental well-being and how community involvement can provide the necessary support to prevent burnout and foster resilience.
Participants will:
- Learn how caregivers of individuals with rare diseases build and maintain supportive communities, both within and across disease types.
- Explore the unique benefits and challenges of in-person versus virtual caregiver networks in providing emotional, informational, and practical support.
- Understand how caregiving impacts mental health and how community involvement can help prevent burnout and foster long-term resilience.
The webinar is expected to run for about 60 minutes.
14
Aug
2025
26
Jun
2025
Palladium is at the heart of breakthrough research shaping a more sustainable and technologically advanced future. This panel brings together leading scientists at the forefront of palladium science to explore its transformative role in catalysis, clean energy, electronic information technologies, environmental protection, and health care. From driving efficient chemical reactions to enabling green energy solutions and medical advancements, palladium’s versatility is unlocking powerful tools for addressing global challenges. Join us as we discuss the latest discoveries, cross-disciplinary collaborations, and real-world applications propelling palladium into the center of tomorrow’s solutions.
Participants will:
- Hear from leading researchers from multiple disciplines who are using palladium to solve global challenges
- Explore palladium-driven advancements in diverse fields, from catalysis to environmental remediation
- Learn about the unique qualities that make palladium an element for innovation.
The webinar is expected to run for about 60 minutes.
26
Jun
2025
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Meet the current and past winners of the Science & PINS Prize for Neuromodulation, learn about the history of the prize, and about our prize partner, PINS Medical.
Prof. Charles A. Nelson receives the 2021 Klaus J. Jacobs Research Prize for his groundbreaking research on the impacts of childhood adversities on brain development, behavioral disorders, and social stability.
Prof. Daniel L. Schwartz receives the 2021 Klaus J. Jacobs Research Prize for his studies addressing cognitive questions through innovative learning experiments, bringing new insight to areas of educational research.
KAUST is an oasis of innovation, advancing science, education, economic development, and entrepreneurism.
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![Science issue cover]()
![Science Advances issue cover]()
![Science Immunology issue cover]()
![Science Robotics issue cover]()
![Science Signaling issue cover]()
![Science Translational Medicine issue cover]()
COVER This illustration shows consecutive stages during operation of a molecular catenating machine. Linking objects through mechanical manipulation is routine at the macroscopic level but remains a major challenge at the molecular scale. Researchers have now developed a light-driven molecular machine that winds two strands into specific entangled structures, which are then transformed into catenated rings. This machine-directed approach creates opportunities to fabricate mechanically interlocked molecules with precise structural control. See pages 454 and 526.
Illustration: C. Bickel/Science
ONLINE COVER Flames burn through the Happy Camp Complex in California. Previous efforts to understand fire start dates focused on the onset of fire-weather, but not the onset of fire season. Madakumbura et al. analyze fire season start dates during 1992–2020 in 13 California ecoregions. Northern California shows an earlier fire season compared to arid southern California. Findings suggest that anthropogenic warming advanced California’s fire season by 6 to 46 days in 11 of 13 ecoregions. This analysis provides a framework for understanding the mechanisms through which climate controls fire onset and improves wildfire season preparedness strategies. Credit: Kari Greer/Planet Pix via ZUMA Wire
ONLINE COVER Treg Cells Help Reverse the Ravages of Time. Mice whose T cells lack the mitochondrial DNA–stabilizing protein TFAM (Tfamfl/flCd4Cre) exhibit multiple pathological features associated with aging for reasons not fully understood. Gómez de las Heras et al. report that Tfamfl/flCd4Cre mice cannot control host–microbiota symbiosis and barrier integrity in the gut. Depletion of gut microbiota or transfer of competent wild-type CD4 T cells, especially regulatory T (Treg) cells, was sufficient to alleviate and delay various facets of multimorbidity in Tfamfl/flCd4Cre mice. T cell immunotherapies that enhance intestinal barrier integrity may therefore be one approach to ameliorate inflammaging. This month’s cover image features an hourglass with beneficial (blue) and pathogenic (orange) microbiota drawn as sand. Transferred Treg cells shown lining the hourglass cause the “sand” to flow in reverse, highlighting their ability to undo some of the effects of inflammaging by restoring gut barrier integrity.
Credit: A. Mastin/Science ImmunologyONLINE COVER Special Issue on Autonomy and AI in Medical Robots. Extending autonomous surgery from simple skills to complicated manipulation tasks is challenging because of the required precision and natural variability in patients. Kim et al. developed a language-guided imitation learning hierarchical framework that includes a high-level policy for task instructions and a low-level policy for trajectory planning and validated the system on ex vivo porcine cholecystectomy surgery. This month’s cover features an image of the end effectors of a surgical robot that autonomously completed the steps involved in the clipping and cutting portion of a cholecystectomy procedure.
Credit: Ji Woong Kim and Xinhao ChenONLINE COVER This week, Restaino et al. show that adjacent sensory neurons cross-communicate with melanoma and head and neck cancers to promote tumor growth and suppress antitumor immunity (see also the Focus by Boyd and Borniger). The image shows staining of sensory nerve tissue called the dorsal root ganglion.
Credit: Eye of Science/Science SourceONLINE COVER Maintaining Maternal Tolerance. Pregnant individuals, like the person shown on the cover, are in a unique immunological situation. Their immune system needs to be tolerant of their semiallogeneic fetus, but still maintain sufficient activity to protect against infection. Li et al. asked whether a population of regulatory CD8+ T cells expressing killer-cell immunoglobulin-like receptors (KIRs) are involved in this balance. The authors found that the peripheral blood of pregnant individuals was enriched in these potently immunosuppressive KIR+CD8+ T cells; this population was further enriched in the blood of mothers carrying male fetuses, possibly due to the need to suppress immune responses to male-specific proteins. Together, these data highlight the importance of immunological balance during human pregnancy and suggest a role for KIR+CD8+ T cells in this balance.
Credit: D-Ozen/iStock